Sensitivity of Two-Tiered Lyme Disease Serology in Children with an Erythema Migrans Lesion.

Amy D Thompson,Fran Balamuth,Desiree N Neville,Laura L Chapman,Michael N Levas,Anupam B Kharbanda,John A Branda,Meagan M Ladell,Claire Loiselle,Lise E Nigrovic

Journal of the Pediatric Infectious Diseases Society（2023）

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摘要

In our prospective cohort of 192 children with a physician-diagnosed erythema migrans (EM) lesion, two-tier Lyme disease serology had higher sensitivity in children with multiple EM lesions (76.8% multiple lesions vs. 38.1% single EM; difference 38.7%, 95% CI 24.8 to 50.4%). The diagnosis of cutaneous Lyme disease should be based on careful physical examination rather than laboratory testing.

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关键词

children, erythema migrans lesion, Lyme disease, serology, disease

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