A porcine model of human-like chronic thromboembolic pulmonary disease.

Simone J Dragsbaek,Mads D Lyhne,Jacob V Hansen,Christina C E Pedersen, Takayuki Jujo-Sanada,Lina Karout,Mannudeep K Kalra,Jens E Nielsen-Kudsk,Asger Andersen

Thrombosis research（2023）

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摘要

•Developing realistic animal models of CTEPD is challenging.•This study developed a porcine model with chronic lesions using autologous emboli.•Histological samples from the model were compatible with CTEPD patients.

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