Application of real-time PCR-based multicolor melting curve with automatic analysis system in pregestational and prenatal thalassemia diagnoses.

Xue-Wei Tang,Fan Jiang,Jian Li,Xiao-Mei Lin,Jian-Ying Zhou,Jun-Hui Wan,Lian-Dong Zuo,Yan-Xia Qu,Fa-Tao Li,Gui-Lan Chen,Dong-Zhi Li

Annals of human genetics（2023）

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摘要

MMCA can be an alternative approach used in routine thalassemia carrier screening and prenatal diagnosis for its high throughput, sufficient stability, low cost, and easy operation.

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关键词

prenatal thalassemia,multicolor melting curve,real‐time pcr–based

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