The Microvascular Health Status Predicts Radio-Induced Acute Toxicities in Breast, Prostate and Head and Neck Cancer Patients

T. Rancati, F. Badenchini,E. La Rocca, F. Pisani, E. Gioscio, L. Possenti, B. Avuzzi,B. Noris Chiorda, C. Giandini, R.R. Colciago,M.C. De Santis, N.A. Iacovelli, M. Franceschini, T. Giandini, A. Cavallo, A. Cicchetti

International journal of radiation oncology, biology, physics(2023)

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摘要
These data suggest an interaction of compromised MV with repair mechanisms. The MVHS model predicts acute toxicity in BC/PC/HN pts proving (i) a quantitative relationship between MV state and radio-susceptibility and (ii) in an organ-agnostic way. The systemic functional information derived by the sublingual microscope could boost the personalization of predictive models and tailor them to the single-patient functional status. Funded by AIRC IG 21479.
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neck cancer,neck cancer patients,radio-induced
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