Up-Regulation of TCF21 Expression Reverses the Malignant Phenotype of Cancer-Associated Fibroblasts in Esophageal Squamous Cell Carcinoma

H. Zhang,J. Yue, L. Qiu, H. Jiang, B. Xia, K. Zhang,M. Zhang,R. Zhou, Z. Yin

International journal of radiation oncology, biology, physics(2023)

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摘要
TCF21 is a determinant of the malignant phenotype of CAFs in ESCC. Up-regulation of TCF21 expression is a promising approach of inhibiting the growth, migration and invasion, activation and radioresistance of CAFs in ESCC.
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关键词
tcf21 expression,squamous cell carcinoma,malignant phenotype,up-regulation,cancer-associated
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