Investigation of plaque psoriasis relapse after secukinumab withdrawal in patients from two Phase 3 studies.

Mark Lebwohl,Lars Iversen,Liv Eidsmo,James G Krueger,Mayte Suárez-Fariñas,Lewis Tomalin,Frank Kolbinger,Ruquan You, Marina Milutinovic

Clinical and experimental dermatology（2023）

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摘要

Following discontinuation of secukinumab, a proportion of patients stayed relapse-free. Further, patients with shorter disease duration remained relapse-free for longer, suggesting that earlier treatment with secukinumab may result in long-term clinical control of moderate-to-severe PsO.

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