Objectively Measured Night-Time Sleep Efficiency and Quality of Life in Patients With Heart Failure With Preserved Ejection Fraction.

Heart failure with preserved ejection fraction (HFpEF) is associated with severely reduced quality of life (QoL). Despite its growing prevalence, efficacious therapeutics to improve QoL remain limited, largely owing to the incomplete understanding of underlying contributors to reduced QoL in patients with HFpEF. 1 Bohmke NJ Billingsley HE Kirkman DL Carbone S. Nonpharmacological strategies in heart failure with preserved ejection fraction. Cardiol Clin. 2022; 40: 491-506 Abstract Full Text Full Text PDF Scopus (0) Google Scholar Sleep efficiency (SE) is a validated metric of sleep quality and effectiveness, and it measures how well a subject uses their time in bed for restorative sleep. 2 Clement-Carbonell V Portilla-Tamarit I Rubio-Aparicio M Madrid-Valero JJ. Sleep quality, mental and physical health: a differential relationship. Int J Environ Res Public Health. 2021; 18: 460 Crossref Scopus (32) Google Scholar SE can be objectively measured with polysomnography but also with actigraphy. Specifically, actigraphy is less intrusive and more cost-effective and is practical for real-time data collection over days or even weeks. 3 Conley S Knies A Batten J et al. Agreement between actigraphic and polysomnographic measures of sleep in adults with and without chronic conditions: A systematic review and meta-analysis. Sleep Med Rev. 2019; 46: 151-160https://doi.org/10.1016/j.smrv.2019.05.001 Crossref PubMed Scopus (67) Google Scholar Poor SE is present in approximately 60% of patients with HFpEF 4 Polanka BM Yanek LR Hays AG Sharma K Shah SJ St-Onge MP Ouyang P Mathews L. The association of multidimensional sleep health with adiposity in heart failure with preserved ejection fraction. Heart Lung. 2023; 58: 144-151 Abstract Full Text Full Text PDF Scopus (0) Google Scholar ; however, whether it influences QoL is not known. This study aimed to investigate the relation between objectively measured night-time SE and QoL in patients with HFpEF. We hypothesized that in patients with HFpEF, decreased SE would be associated with worse QoL.