Cyp2d6 metabolizer phenotype predicts aripiprazole pharmacokinetics in children and adolescents

Eliah J. Hiken,Ethan A. Poweleit, Corey Keane,Zeruesenay Desta,Jeffrey R. Strawn,Laura B. Ramsey

JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY（2023）

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摘要

The objectives of this presentation are to evaluate the impact of the cytochrome P450 enzyme, 2D6 (CYP2D6) phenotype on aripiprazole and dehydroaripiprazole pharmacokinetics in youth.

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