The effect of PLK1 inhibitor in Osimertinib resistant NCI-H1975 cell lines.

Xiaoyang Dai, Xiangning Liu,Fujing Ge,Hongdao Zhu,Churun Zheng,Fangjie Yan,Bo Yang

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences（2023）

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摘要

PLK1 inhibitors combined with Osimertinib behave stronger anti-tumor effect to Osimertinib-resistant NSCLC cells and may be used for intervention and treatment of Osimertinib resistance.

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关键词

Bioinformatics,Drug combination,Drug resistance,Non-small cell lung cancer,Osimertinib,PLK1 inhibitors

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