Synthesis, structure and antimicrobial activity of sterically hindered bis-phosphonium derivatives of 2,6-di-tert-butyl-4-methylphenol

Mendeleev Communications(2023)

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摘要
New biologically active quaternary bis-phosphonium salts were obtained by quaternization of 4-bromomethyl-2,6-di-tert-butylphenol with several α,ω,-bis(diphenylphosphino)-alkanes. All synthesized compounds demonstrated high antibacterial and antifungal activities against pathogenic microflora of humans and animals.
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关键词
quaternary phosphonium salts, 2, 6-di-tert-butyl-4-methylphenol, sterically hindered phenols, antibacterial activity, antifungal activity
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