Editorial: Ex vivo graft preservation and modification

Organ transplantation is the best treatment for end-stage organ disease. However, the demand 53 for suitable organs for transplant outweighs the supply, which has led to the expansion of the 54 donor pool using marginal quality organs 1 . With respect to kidneys, marginal organs may carry 55 higher risks, but they have been shown to be better for patients than dialysis 2,3 . To mitigate the 56 risks associated with marginal organs ex vivo machine perfusion has been implemented for a 57 variety of solid organs