Antioxidant and anti-lipase capacities from the extracts obtained from two invasive plants: Ambrosia artemisiifolia and Solidago canadensis

Ambrosia artemisiifolia and Solidago canadensis are invasive plants with adverse ecological, socio-economic, and health impacts. After management operations, the plant waste can represent a definite opportunity for the circular economy. To that end, an evaluation of their chemical compositions using UHPLC-MS was carried out. We also investigated their antioxidant capacities (DPPH center dot, ABTS center dot+, CUPRAC, FRAP and iron chelation) and, for the first time, their anti-lipase properties using capillary electrophoresis. The extracts mainly contained two compounds: 5-O-caffeoylquinic acid and 3,5-dicafeoylquinic acids. Notably, S. canadensis is characterized by the presence of two additional compounds, 3,4-dicaffeoylquinic and 4,5-dicaffeoylquinic acids, which are abundant in its roots, as well as quercitrin in its aerial parts. The findings revealed significant antioxidant capacities. Specifically, with the DPPH center dot assay, the aerial part of S. canadensis exhibited stronger antioxidant activity than that of A. artemisiifolia at every tested concentration. At 50 mu g/mL, the percentages of inhibition DPPH center dot were 24.3 +/- 3.2% and 56.7 +/- 3.4% respectively. At the same concentration, the root parts were marginally less active than the aerial parts. By HPTLC-DPPH, the main antioxidant markers were highlighted. S. canadensis was a better anti-lipase agent than A. artemisiifolia with enzymatic inhibition percentages of 82.3 +/- 0.2% and 49.6 +/- 5.9% respectively (at 100 mu g/mL). The two acids present in all the crude extracts were tested separately as pancreatic lipase inhibitors. In conclusion, these plants could potentially be utilized for mitigating various pathologies arising from oxidative stress, including obesity.