Metabolomics-based Alleviation of Depression by Xiaoyaosan Through Regulation of XDH and GRIA2

Chaofang Lei,Yueyun Liu,Qingyu Ma,Zhigang Chen,Qingmei Kong,Yanbin Jia,Xihong Wang, Xiaojuan Li,Zhe Xue,Jiaxu Chen

Pharmacological research Modern Chinese medicine（2023）

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摘要

•Xiaoyaosan effectively regulates metabolic disorders in patients with mild to moderate depression.•Xiaoyaosan demonstrates the ability to regulate metabolic disorders in depressed rats.•The administration of Xiaoyaosan results in the up-regulation of XDH and GRIA2 expression in CUMS rats.

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Xiaoyaosan,Depression,Metabolomics,XDH,GRIA2

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