MALDI Mass Spectrometry Imaging and Semi-Quantification of Topically Delivered Lactic Acid.

Aaron Cohen,Raphael Legouffe,Junhong Mao,Mathieu Gaudin,David Bonnel

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)（2023）

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摘要

The combination of L-Lactic acid- C and MALDI-MSI was successfully used to quantitatively and qualitatively measure the topical delivery of lactic acid from a variety of skincare products. This approach could be used in future work to better understand the mode of action of lactic acid as an active ingredient in skincare products.

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关键词

cationic xylene, chemical peels, derivatization, Franz cell, isotope labeling, stratum corneum, trichloroacetic acid

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