Extent of Surgical Resection as a Predictor of Tumor Progression in Skull Base Chordomas: A Multi-Center Volumetric Analysis.

Skull-base chordomas can be challenging to resect. Even though maximal resection and radiotherapy improve rate of tumor progression, many of these lesions eventually recur. We have identified a post-operative tumor volume of ≥4.9cm and extent of resection of ≤81.3% in this cohort as predictors of progression in patients receiving SoC.