Intracellular Zn(II) Induced Turn-on Fluorescence of an L-phenylalanine-derived Pseudopeptide.

Arpna Tamrakar,Praveen Kumar,Neha Garg,Santiago V. Luis,Mrituanjay D. Pandey

Organic & biomolecular chemistry（2023）

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摘要

A C2 symmetric L-phenylalanine-derived pseudopeptide has been synthesized for selective and sensitive recognition of Zn(II) ions in aqueous-organic media. The pseudopeptidic probes exhibit intracellular Zn(II) ion-sensing capabilities as demonstrated via live-cell fluorescence studies on RAW264.7 cells. Hence, we present a bioinspired pseudopeptide for potential biological applications involving intracellular Zn(II) ion detection.

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