Impaired immune responses and prolonged viral replication in lung allograft recipients infected with SARS-CoV-2 in the early phase after transplantation.

Olaf M Glueck,Xiaoling Liang,Irina Badell,Paul R Wratil,Alexander Graf,Stefan Krebs,Helmut Blum,Johannes C Hellmuth,Clemens Scherer,Alexandra Hollaus,Patricia M Spaeth,Burak Karakoc,Thimo Fuchs,Julia Zimmermann,Teresa Kauke,Andreas Moosmann,Oliver T Keppler,Christian Schneider,Maximilian Muenchhoff

Infection（2023）

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摘要

Patients in the early phase following lung allograft transplantation are vulnerable to infection with SARS-CoV-2 due to impaired immune responses. This patient population should be vaccinated before LuTx, protected from infection post-LuTx, and in case of infection treated generously with currently available interventions.

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