Cholangiocarcinoma Surveillance Recommendations in Patients with Primary Sclerosing Cholangitis
CLINICS IN LIVER DISEASE(2024)
摘要
Cholangiocarcinoma (CCA) is a deadly complication observed in the setting of primary sclerosing cholangitis (PSC). When symptoms develop and CCA is diagnosed, it is usually at an advanced stage. Median survival is less than 12 months. Early identification of CCA leads to improved outcomes. Although diagnostic tests have excellent specificity, they are plagued by low sensitivity. No surveillance strategies have been widely agreed upon, but most societies recommend measurement of serum carbohydrate antigen 19-9 and MRCP every 6 to 12 months in patients with PSC. Advances in understanding of the genetic factors that lead to CCA are awaited.
更多查看译文
关键词
Primary sclerosing cholangitis,Cholangiocarcinoma,Screening,Surveillance,CA 19-9,MRCP
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要