Imipramine-imprinted polymer: Designing by theoretical and empirical studies

Monika Sobiech,Dorota Klejn, Wojciech Kleniewski,Piotr Luliński,Joanna Giebułtowicz

MICROCHEMICAL JOURNAL（2023）

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摘要

•Composition optimization of imprinted sorbent specific towards imipramine was performed.•Theoretical analysis was applied to explain selectivity of imprinted materials.•The highest binding capacity was noted for imipramine and its analogs in competitive studies.•Solid phase extraction protocol on imprinted sorbent was optimized.

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关键词

Imipramine,Molecular modeling,Molecularly imprinted polymer,Solid phase extraction,Desipramine

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