Additive Manufacturing of Bioresorbable Scaffolds Based on Polycaprolactone and Composites

Scaffolds made of high-molecular-weight PCL, were fabricated using FDM 3D printing method for potential biomedical applications. A series of experiments were conducted to evaluate the rate of biodegradation and biocompatibility. It was found that after 200 days of immersion in simulated body fluid (SBF), the overall mass loss of the scaffold was approximately 1.3 $\Delta \mathrm{m}$ , %. Additionally, fragments of pure PCL, were modified using low-temperature plasma to achieve more hydrophilic properties. The surface wettability was assessed using the sessile drop method. The contact angle of the unmodified PCL, was approximately $72-72^{\circ} (\pm 2)$ . Treatment with low-temperature plasma resulted in the creation of a hydrophilic layer on the scaffold surface.