The relationship between body mass index and mortality is not linear in patients requiring venovenous extracorporeal support

Advancing age and higher CCI are each associated with increased risk for mortality in patients requiring VVECMO. A non-linear relationship exists between mortality and BMI and those between 32 and 37 have lower odds of mortality than those between BMI 25 to 32. This nonlinear pattern suggests a need for further adjudication of the contraindications associated with VVECMO, particularly those based solely on BMI.