Ondansetron Blocks Wild-Type and P.f503l Variant Small-Conductance Ca2+-activated K+ Channels

Jong Soo Ko,Shuai Guo,Jonathan Hassel,Patrícia B. S. Celestino-Soper,Ty C. Lynnes,James E. Tisdale,James J. Zheng,Stanley Taylor,Tatiana Foroud,Michael D. Murray,Richard J. Kovacs,Xiaochun Li,Shien‐Fong Lin,Zhenhui Chen,Matteo Vatta,Peng‐Sheng Chen,Michael Rubart

PMC（2018）

引用 18|浏览9

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摘要

We showed that ondansetron, a 5-HT3 receptor antagonist, blocks small-conductance Ca2+-activated K+ (SK) current. Ondansetron may be useful in controlling arrhythmias in which increased SK current ...

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