Abstract 15977: A Stabilizing Variant in Transthyretin, T119M, and Risk of Ischemic Vascular Disease

Louise Stig Hornstrup,Ruth Frikke‐Schmidt,Børge G. Nordestgaard,Anne Tybjærg‐Hansen

Circulation（2012）

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摘要

Background: Senile systemic amyloidosis, which clinically may present as ischemic vascular disease, is a common aging phenomenon caused by deposition of wildtype transthyretin (TTR) fibrils mainly ...

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transthyretin,vascular

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