Prolonged Viral Shedding and Multiple Admissions Due to SARS-CoV-2-Associated Pneumonia in a Patient with Chronic Lymphocytic Leukemia: A Case Report

Sergio España-Cueto, Jose Ramon Santos, Oscar Blanch-Lombarte, Joan-Ramón Grifols, Gemma Lladós, C. López, Daniel Molina-Morant, María Nevot,Edwards Pradenas,Benjamín Trinité, Esther Jiménez-Moyano,Ruth Pena,Sílvia Marfil,Mariona Parera, Francesc Catala, Águeda Hernández-Rodríguez, A. Escalas,Ignacio Blanco,Veronica Saludes,Elisa Martró,Carla Rovirosa,Eva Riveira-Muñoz, T. Puig,Christelle Ferrà, Carmen Fernandez-Arias,Julià Blanco,Ester Ballana,Bonaventura Clotet, Pere J Cardona,Marc Noguera-Julián, Julia García-Prado,Lourdes Mateu,Marta Massanella,Roger Paredes

Journal of biomedical research & environmental sciences（2022）

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摘要

We describe a case of a patient who experienced recurrent COVID-19 pneumonia over a period of 123 days. Neither remdesivir nor convalescent plasma were temporally associated with viral clearance or increased plasma neutralization capacity. Antibody levels remained low until day 151 and cellular immunity increased overtime with no viral evolution.

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chronic lymphocytic leukemia,pneumonia,viral shedding,sars-cov

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