Rational design of keratin nanoparticles utilizing diverse hair protein fractions for controlled drug release

Liong-Rung Liu,Mao-Cong Huang, Zheng-Jie Lee,Yang Wei

Journal of The Taiwan Institute of Chemical Engineers（2023）

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摘要

•KAPs/KIFs ratios affect keratin nanoparticle structure and properties.•Higher KAPs proportions reduce particle aggregation.•More KIFs yield smaller particles and enhanced theophylline release.•Fine-tuning drug release necessitates adjusting KAPs and KIFs ratios.

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关键词

Keratin-associated proteins,Keratin intermediate filament,Nanoparticle,Human hair,Theophylline

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