Retrospective Cohort Study of Methotrexate Use in the Treatment of Pediatric Crohnʼs Disease

Whitney M. Sunseri,Jeffrey S. Hyams,Trudy Lerer,David Mack,Anne M. Griffiths,Anthony Otley,Joel R. Rosh,Ryan Carvalho,Andrew B. Grossman,José Cabrera,Marian D. Pfefferkorn,James Rick,Neal S. LeLeiko,Meredith C. Hitch,Maria Oliva-Hemker,Shehzad Ahmed Saeed,Michael D. Kappelman,James Markowitz,David J. Keljo

Inflammatory Bowel Diseases（2014）

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摘要

BackgroundMethotrexate (MTX) use as an alternative to thiopurines in the treatment of Crohn's disease (CD) in children is increasing. This study was undertaken to assess safety and efficacy of MTX in children with CD.

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关键词

methotrexate use,retrospective cohort study

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