Ameliorative and protective effect of Bergenia ciliata (Haw.) Sternb. extract against acetaminophen-induced hepato-renal damage in rats: B. ciliata and hepato-renal damage

Makhmoor Ahmad Bhat,Rajinder Raina,Pawan Kumar Verma,Shilpa Sood,Zuhaib F. Bhat

Phytomedicine Plus（2024）

引用 0|浏览3

暂无评分

摘要

•High dose of APAP induced hepatic and renal impairment in rats.•B. ciliata extract alleviated APAP-induced altered biochemical and oxidative indices.•The extract also reversed the histopathological alterations in erythrocytes, liver and kidney.•The presence of antioxidants in the extract afforded protection to the liver and kidney.

查看译文

关键词

Abbreviations:Acetaminophen,Hepato-renal damage,Rats,Bergenia ciliata (Haw.) Sternb.,Hepatoprotection,Nephroprotection Abbreviations: APAP,alanine aminotransferase, ALT,albumin, AL,albumin/globulin ratio, A/G ratio,alanine aminotransferase, SGPT,alkaline phosphatase, ALP,aspartate aminotransferase, AST,aspartate aminotransferase, SGOT,blood urea nitrogen, BUN,blood glutathione, GSH,body weight, BW,glutathione peroxidase, catalase, CAT,creatinine, CR,median effective concentration, EC50,gallic acid equivalents, GAE,gamma-glutamyl transferase, GGT,glutathione peroxidase, GPx,globulin, GB,glucose-6-phosphate dehydrogenase, G6PD,glutathione-s-transferase, GST,malondialdehyde, MDA,reactive nitrogen species, RNS,reactive oxygen species, ROS,superoxide dismutase, SOD,total plasma proteins, TP,total thiols, TTH

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要