Genome-edited rabbits: Unleashing the potential of a promising experimental animal model across diverse diseases
ZOOLOGICAL RESEARCH(2024)
摘要
Animal models are extensively used in all aspects of biomedical research, with substantial contributions to our understanding of diseases, the development of pharmaceuticals, and the exploration of gene functions. The field of genome modification in rabbits has progressed CRISPR/Cas9-related technologies, have catalyzed the successful development of various genome-edited rabbit models to mimic diverse diseases, including related ailments, neurological diseases, and ophthalmic future potential in translational medicine.
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关键词
Genome editing,Animal model,Rabbit,CRISPR/Cas9,Genetic diseases
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