Clinical and Perceptual Improvements in Skin Hydration and Barrier Strength Delivered by a Gel Matrix Moisturizer

Background: Skin conditions such as atopic dermatitis and rosacea are associated with skin barrier disruption, which can manifest clinically as dry, rough skin. The dynamic moisture barrier maintains skin hydration by adapting to internal and external conditions to regulate water throughout the stratum corneum (SC). Critical for maintaining hydration and barrier function are aquaporin-3 and filaggrin.