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Molecular Characteristics of Advanced/recurrent Endometrial Cancer Patients with Non-Specific Molecular Profile (1302)

Gynecologic oncology(2023)

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摘要
Molecular classification over histology is increasingly important in the management of endometrial cancer. The Cancer Genomic Atlas (TCGA) established four genomic groups of endometrial cancer. The non-specific molecular profile (NSMP) or copy number low (CNL) subtype emerged as a heterogenous group with an intermediate prognosis. The objective of this study was to characterize the cohort of NSMP patients with regard to identifiable targetable mutations.
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