Diffusion MRI-based Connectivity Enriched with Microstructure Information Predicts the Propagation of Cortico-Cortical Evoked Potentials
HAL (Le Centre pour la Communication Scientifique Directe)(2020)
摘要
Propagation of Cortico-Cortical Evoked Potentials (CCEPs) varies depending on numerous structural features of brain tissue. In this work, we show that dMRI-based connectivity enriched with microstructure data has the potential to measure cortico-cortical communication as it predicts CCEP-based effective connectivity. Our multiple linear regression model incorporates q-space indices like Q-space Inverse Variance, Non-Gaussianity and Return to Plane Probability with minimum streamline lengths obtained from tractography to predict delays and amplitudes of the N1 peaks in CCEPs. In our experiment, we use presurgical dMRI and intrasurgical ECoG recordings of 9 patients operated on brain tumor in the awake condition.
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关键词
diffusion,microstructure information predicts,connectivity enriched,mri-based,cortico-cortical
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