Meme kanseri tedavisinde yeni bir yaklaşım: hedefledirilmiş nanotaşıyıcı sistemler

Cancer is one of the most prevalent diseases in the world. Breast cancer is the second most deadly cancer type after lung cancer. Surgical intervention, chemotherapy and radiotherapy are the most used conventional methods in the treatment of breast cancer. The non-targeted approach of conventional treatments causes serious side effects in healthy cells and tissues, and often mortality is due to the side effects of these conventional treatments. In recent years, nano-sized particles called drug delivery systems targeting cancer cells have attracted attention as a new approach in cancer treatment. The fact that these nanocarrier systems target tumor cells without damaging healthy tissues has been a hope for breast cancer. Moreover, nanocarriers are unique biomaterials that may exhibit low toxicity, high biocompatibility, biodegradability, ease of use, high dose drug loading, and adjustable surface functionalities. In the present study, we summarize recent studies of nanocarriers that offer a critical review of an alternative strategy to breast cancer therapy.