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Age in Impacting the Occurrence of Chronic Diseases: Case of Recurrently Diagnosed Diseases at Korhogo Regional Hospital in Northern of Cote D’ivoire

Computational biology and bioinformatics(2022)

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Abstract
Background: Our previous study suggested Korhogo district as strongly influenced by parasitical and infectious diseases and as well high blood pressure (HBP) troubles.In the same study, we shown that recurrently diagnosed diseases at Korhogo Regional Hospital (KRH) clustered in two group, depending on the regular and/or irregular dynamism of their increasing.Diseases with regular increasing dynamism (i.e.hypertension) claiming to be chronic diseases were controlled by patients' anthropomorphic parameters such as age and weight as opposite to diseases with irregular increasing frequency dynamism dominated by malaria and influenza (infectious and tropical diseases).Basing on these results, we embarked here in assessing the relationship between age anthropomorphic parameter and the occurrence of recurrently diagnosed diseases at KRH. Methods: Patients clinical and anthropomorphic parameters data (i.e.age and weight), collected from 2014 to 2018 at the general medicine division of KRH, were subsequently structured and submitted to a multivariate computational statistical analysis in R programming environment.Results: Our findings showed the strong influence of aging on the occurrence of all recurrent listed and analyzed pathologies recorded at KRH from 2014 to 2018 and in particular, on chronic diseases such as cardiovascular troubles dominated by high blood pressure (HBP), osteo-articular/muscular, metabolic diseases (diabetes) and digestive troubles.Conclusion: Considering as a whole, even if our study supported a high concordance between aging and occurrence of diseases recurrently recorded at KRH, it is noteworthy to underline the significant correlation between aging (age increasing) and chronic diseases occurrence.This trend results accentuated for chronic diseases, i.e. high blood pressure, osteoarticular and muscular diseases for age over 50 years.
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