Role of plant polysaccharides in pharmaceutical hydrogels

Hydrogel is a three-dimensional polymer with water molecules trapped within the structure. It is mainly obtained from biological or nonbiological polymers. These polymeric structures are mainly divided into two types: physical gel (developed by covalent linkage) and chemical gel (developed by ionic cross linkage). Among all polysaccharides, we mainly focused on the synthesis of plant-derived plant polysaccharides (cellulose, starch, pectin, gum acacia, gum Arabic, gum ghatti, gum karaya, gum tragacanth, locust bean gum, and sterculia gum)-based HDG using ammonium persulfate, methylene-bis-acrylamide, and other important factors (pH, reaction time, irradiation of gamma and microwave rays) loaded with various drug molecules (keratin, zaltoprofen, doxorubicin, beta carotene, amoxicillin, ampicillin, guaifenisin, albumin, tetracycline, ibuprofen, laccase enzyme (probiotic), silver, folic acid, 5-flurouracil, ropinirole, paracetamol, aspirin, glipizide, mupirocin, ketoprofen, citicoline, and insulin) targeted as targeted drug delivery system, improvised anticancer activity (cervical cancer, pancreatic cancer, etc), antibacterial activity (Staphylococcus aureus, Salmonella species, P. aeruginosa, B. cereus, S. typhirium, L. monocytogenes, E. coli) and wound healing property. These data confirmed the pharmaceutical applicability spectrum of different plant polysaccharide-based hydrogel.