Steroid challenge: Response to dexamethasone implant in persistent, simple central serous chorioretinopathy

A male in his 30s was diagnosed with acute central serous chorioretinopathy (CSC) in the left eye for 3 months and after an unsuccessful oral eplerenone therapy presented with persistent disease. Continuing vision blur, worsening subretinal fluid, and absent fluorescein leak on angiography prompted us (based on earlier experience) to use the novel therapy of dexamethasone intravitreal implant. Successful resolution was noted in 2 months with visual improvement. We describe the first use of an intravitreal long-acting corticosteroid implant in a case of persistent, simple CSC with a favorable outcome.