Cross-State Variations and time Trends in Opioid use Disorder among a Privately Insured Nonelderly Population in the United States.

Objectives: To describe cross-state variations and time trends in Opioid Use Disorder (OUD) among privately insured individuals in the U.S. from 2005-2015 and investigate the demographic differences between OUD patients in states most affected by the epidemic compared to the remaining states.