3D Bioprinting of Neurovascular Tissue Modeling with Collagen‐Based Low‐Viscosity Composites (Adv. Healthcare Mater. 25/2023)

3D Bioprinting In vitro neurovascular unit (NVU) models are valuable for investigating brain functions and developing drugs. However, it remains challenging to recapitulate the native architectural features and ultra-soft extracellular matrix (ECM) properties. In article 2300004, Ling Wang, Dichen Li, and co-workers propose a novel two-stage bioprinting methodology with collagen-based low-viscosity composites, for functional 3D neurovascular constructs modeling in vitro with low modulus of ECM and high fidelity. The model shows selective barrier properties and distinct expression of critical proteins.