Bilateral Macular Telangiectasias with Macular Edema in a Patient on Incessant Diethylcarbamazine Medication – A Case Report

Macular telangiectasia is characterized by bilateral alterations of the macular capillary network and neurosensory atrophy, but it is very rarely associated with macular edema. Presented here is a case with bilateral macular capillary telangiectasias with severe macular edema and subretinal fluid accumulation. Here, a proposed mechanism for the injury to the capillaries, causing telangiectasias and edema, is the toxicity of drug diethylcarbamazine, which the patient had been self-administering for lymphatic filariasis for 20 years. The drug at increased concentrations is known to accentuate free radical–mediated cellular injury by inhibiting the lipooxygenase pathway.