Functional Bioadaptability in Medical Bioceramics: Biological Mechanism and Application

The question of what qualities excellent medical bioceramics must possess to ensure satisfactory prognosis for bone healing and reconstruction remains a topic of great interest in both clinical and biomaterial sciences. Our team has been dedicated to researching medical bioceramics since the 1990s, involving basic scientific research, applied translational research, and clinical trials. Consequently, we have amassed a wealth of research and implementation experience. In this article, we aim to explore the subject of "Functional Bioadaptability in Medical Bioceramics", specifically focusing on calcium phosphate-based materials. We summarized how to effectively combine bioadaptability with design and manufacturing of medical bioceramics in the background of orthopedic clinical application, with the following aspects of structural adaptability, degradative adaptability, mechanical adaptability, and application adaptability. Hopefully, some suggestions put forward can ultimately provide valuable insights and recommendations for the design, production, supervision, and application of the upcoming medical bioceramics.