Analysis of 125 patients with endoscopically diagnosed human intestinal spirochetosis

Aims Human intestinal spirochetosis (HIS) is defined by the presence of a layer of spirochetes attached by one cell end to the colorectal epithelium. Brachyspira species are the etiologic agents responsible for HIS. While many patients with HIS have no symptoms, some have chronic diarrhea and bloody stool. There is little known about pathogenicity of HIS, and awareness is still low. The characteristics of patients treated for HIS were reviewed.