Use of a high flow nasal cannula in extremely premature infants: Benefits and drawbacks

This research paper provides a comprehensive review of the utilization of high-flow nasal cannula (HFNC) therapy as a means of respiratory support in extremely premature infants. The paper elucidates the underlying mechanisms of HFNC, which encompass the provision of distending pressure, reduction of respiratory effort, facilitation of carbon dioxide elimination, and optimization of gas conditioning. Noteworthy advantages of HFNC in comparison to invasive ventilation include enhanced oxygenation, improved lung compliance, and promotion of bonding, while simultaneously mitigating the occurrence of complications. Nevertheless, it is important to acknowledge potential drawbacks associated with HFNC, such as heightened morbidity, inadequate support necessitating reintubation, and an elevated risk of air leaks. Further investigations are imperative to refine HFNC protocols, conduct comparative analyses with alternative interventions, and enhance overall patient outcomes. In summation, HFNC represents an efficacious noninvasive respiratory treatment modality for premature infants, albeit with certain limitations. The optimization of benefits can be achieved through meticulous monitoring and standardization of practices.