Baseline characteristics associated with the incidence of intraocular inflammation after the intravitreous injection of brolucizumab

International Ophthalmology(2023)

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摘要
To investigate baseline characteristics associated with the incidence of intraocular inflammation (IOI) after the intravitreal injection of brolucizumab (IVBr) for the treatment of neovascular age-related macular degeneration (nAMD). This retrospective study included 66 eyes of 62 consecutive patients with nAMD who received IVBr (18 eyes were treatment naïve and 48 eyes had switched from other anti-vascular endothelial growth factor [VEGF] therapy). Baseline clinical characteristics were compared in non-IOI and IOI groups. Although a dry macula was achieved at a high rate even 6 months after IVBr, IOI occurred in 8 of 66 eyes (12.1
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关键词
Brolucizumab,Age-related macular degeneration,Intraocular inflammation,Laser flare-cell photometry,Anti-vascular endothelial growth factor
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