Testing 2 Alternative Time Trade-Off Methods for Valuation of Children’s Health States

•Time trade-off (TTO) values of children’s health states can be elicited by asking respondents to assume that the health states are experienced by their siblings, children, or grandchildren and to trade their own life-years for the health of the children.•TTO values of EQ-5D-Y-3L health states derived from lag-time TTO and composite TTO methods differ in values and distributions.•The issue of “unwillingness to trade” previously observed in TTO valuation of EQ-5D-Y-3L health states may be mitigated by using alternative designs such as lag-time TTO and caregiver TTO.