90Y-/166Ho- ‘Radiation lobectomy’ for liver tumors induces abnormal morphology and impaired drainage of peritumor lymphatics

Daan Andel,Lotte van den Bent, Marnix Gerard Ernest Hendrik Lam,Maarten Leonard Johannes Smits,Isaac Quintus Molenaar,Joep de Bruijne,Miangela Marie Laclé,Onno Kranenburg, Inne Hildbrand Max Borel Rinkes,Jeroen Hagendoorn

JHEP Reports（2024）

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摘要

•Peritumoral liver lymphatics are tortuous, thickened and discontinuous after radioembolization.•Irradiated liver lymphatics are ectactic, indicating lymph stasis within the liver.•In vivo lymphangiography reveals reduced lymph drainage from radioembolized liver lymphatics into perihilar lymph nodes and vessels.

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关键词

Lymphatics,Radiation lobectomy,Radioembolization,Intraoperative liver lymphangiography,hcc,crlm,Immunohistochemistry

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