Photoredox-Catalyzed Defluorinative Carboxylation of gem-Difluorostyrenes with Formate Salt

Chao Sun, Quan Zhou,Chuan-Ying Li,Zhong-Wei Hou,Lei Wang

ORGANIC LETTERS(2024)

引用 0|浏览0
暂无评分
摘要
Herein, we present a transition-metal-free, easy handling protocol for regioselective carboxylation of gem-difluorostyrenes with sodium formate as the C1 source. 30 examples of alpha-fluoracrylates were obtained in yields of 30 to 80% under these conditions. A defluorinative monofluorovinyl intermediate and consecutive photoinduced electron transfer mechanism were proposed after mechanism investigation.
更多
查看译文
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要