Pain Management in Burn Patients Pharmacologic Management of Acute and Chronic Pain

center dot Burn-related pain should be assessed first by chronicity (acute or chronic), followed by type(nociceptive, neuropathic, nociplastic) to guide multimodal pharmacologic management in a stepwise algorithm approach. center dot Multimodal pharmacologic management includes knowledge and understanding of pharmacokinetics, pharmacodynamics, pharmaco economics, pharmacogenomics, and pharmacotherapeutics. center dot Combination therapy increases efficacy and reduces toxicity by offering a multimodal approach to burn-related pain by targeting different receptors in the PNS and CNS. center dot Responses to multimodal pharmacologic management should frequently be assessed usingthe numerical rating scale (NRS) for pain(mild51-3; moderate54-6; severe57-10). center dot Consider etiologies of burn-related pain that may be amenable to surgical interventions orchronic pain states that may require a referral to pain management