Concurrent use of statins in patients undergoing curative intent treatment for triple negative breast cancer: A systematic review and meta-analysis.

Tyler McKechnie, Zachary Brown,Olivia Lovrics,Shuling Yang,Cagla Eskicioglu,Elena Parvez

Clinical Breast Cancer（2023）

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摘要

•Statins are a low-risk and cost-effective intervention with great potential.•Using statins with TNBC therapy may offer long-term oncologic benefits.•Using statins with TNBC therapy may improve five-year disease-free survival.•No significant difference in five-year overall survival with concurrent statin use.•High risk of bias found in current evidence supporting statin use in TNBC therapy.

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关键词

Breast Cancer,Triple Negative Breast Cancer,HMG-CoA Reductase Inhibitors,Surgical Oncology

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