A novel lanthanide metal-organic frameworks as a luminescent sensor for efficient detection of riboflavin

Rational design of highly sensitive and rapid fluorescent probes is a major concern of analytical methods. Here, we synthesized two Ln-PFTA with different metal nodes (Dy, Sm) by simple hydrothermal self-assembly using 3-fluorobiphenyl-3 ',4,5 '-tricarboxylic acid (H2PFTA) as ligand. As a ratio sensor for detecting riboflavin (RF), it has self-calibration effect, ultra-low detection limit (0.225 nM), excellent durability, and high selectivity. In order to add practicality, even in actual samples (fetal bovine serum, tablets, and milk), the recovery rate is as high as 92%-104%, which is considered to be an excellent luminescent sensor for detecting RF. According to the survey, there are few studies on the detection of RF by fluorescence spectroscopy. In addition, there is fluorescence resonance energy transfer (FRET) between the processes of Ln-PFTA detecting RF, and the peak intensity change of Ln-PFTA is attributed to its modulated luminescence characteristics. At the same time, it also shows the best FRET efficiency for detecting RF. A simple and reliable new sensing Ln-MOF was successfully synthesized by solvothermal method, which showed excellent sensitivity and selectivity to riboflavin (RF).image