Gynecologic Clear Cell Carcinoma and Paraneoplastic Cerebellar Degeneration: A Literature Review and Case Study

• Paraneoplastic cerebellar degeneration (PCD) is rare condition associated with gynecologic malignancy. • PCD presents with progressive cerebellar dysfunction in the setting of malignancy and confers a poor neurologic prognosis. • PCD associated with ovarian clear cell cancer may have more favorable neurologic outcomes versus other histologies. • The mainstay of PCD treatment is treatment of malignancy; symptom management may improve quality of life.