A novel fluorescence probe for ultrafast detection of SO2 derivatives/biogenic amines and its multi-application: Detecting food and fish freshness, fluorescent dye and bioimaging

In this study, we have effectively prepared a novel fluorescent probe named HDXM based on benzopyran derivatives for the ultrafast detection (within 3s) of SO2 derivatives or biogenic amines. HDXM showed a noticeable color change after the addition of SO2 derivatives (from purple to colorless) or biogenic amines (from purple to blue), indicating that HDXM can identify two analytes with the naked eye. It is worth noting that HDXM can be used to detect SO2 derivatives in actual sugar samples, and to image HSO3−/SO32− in living cells. More importantly, sensing labels (HDXM-loaded filter paper or agarose hydrogel) enable real-time visual monitoring of salmon freshness through colorimetric and fluorescence dual channels. Compared with the Chinese national standard method, the sensing label is an effective tool for evaluating the freshness of fish. Benefiting from its excellent solubility and fluorescence performance, HDXM can be used as a versatile fluorescent material in various applications, including flexible films, glass coatings, impregnating dyes, printing, and fingerprint ink. HDXM is expected to be a promising and valuable multifunctional tool for food safety and fluorescent materials. Environmental Implication Bisulfite (HSO3-) has long been considered as hazardous environmental pollutant, while biogenic amines (BAs) are ubiquitous in organisms, which have adverse effects on human body and environment. In this paper, a novel probe for colorimetric and fluorescent sensing HSO3- and BAs with ultrafast response is synthesized. Fluorescence change is occurring PET or enhancing ICT process. Probe can image or detect HSO3- in living cells and sugar samples. Indicator labels loaded with probe can visually monitor fish freshness in real-time. Probe can also be developed as a dye into a variety of fluorescent materials. This research can reduce environment-related health risks.